Ibisobanuro bigufi:
Numero ya CAS: 1197-18-8
Inzira ya molekulari: C8H15NO2
uburemere bwa molekile: 157.21
Imiterere ya shimi:
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Acide Tranexamic |
| Icyiciro | Icyiciro cyo kwisiga |
| Kugaragara | Ifu yera cyangwa hafi yera, ifu ya kristu |
| Suzuma | 99% |
| Ubuzima bwa Shelf | Imyaka 2 |
| Gupakira | 25kg / ingoma |
| Ibikoresho bya Shimi | Irashobora gushonga kubusa mumazi no muri acide glacial acetique kandi irashobora gushonga cyane muri Ethanol kandi ntigishobora gushonga muri ether |
Ibisobanuro
Acide Tranexamic ni inkomoko ya aside aminomethylbenzoic, hamwe nubwoko bwa antifibrinolytique kugirango ihagarike kuva amaraso. Uburyo bwa hemostasis ya acide tranexamic isa na aside aminocaproic na aside aminomethylbenzoic, ariko ingaruka zirakomeye. Imbaraga ninshuro 7 kugeza 10 za acide aminocaproic, inshuro 2 za aside aminomethylbenzoic, ariko uburozi burasa.
Imiterere yimiti ya acide tranexamic isa na lysine, kubuza guhatanira plasmin yumwimerere muri fibrin adsorption, kugirango ikumire gukora, poroteyine yo kurinda fibre itangirika na plasmin no gushonga, amaherezo igera kuri hemostasis. Bikoreshwa mukuvura acute cyangwa karande, yibanze cyangwa sisitemu yibanze ya fibrinolytic hyperthyroidism iterwa no kuva amaraso, nko kuva amaraso kubyara, kuva amaraso yimpyiko, kuva amaraso ya hypertrophyie ya prostate, hemophilia, igituntu cyigituntu, amaraso, igifu, nyuma yo gukora umwijima, ibihaha , intanga nizindi mitsi ya viscera; irashobora kandi gukoreshwa mububaga mugihe amaraso adasanzwe nibindi ..
Acide Clinical tranexamic igira ingaruka zikomeye kuburwayi bwudukoko, dermatite na eczema, purpura yoroshye, urticariya idakira, urticaria yimibonano mpuzabitsina, guturika uburozi no guturika. Kandi ifite n'ingaruka runaka kuri erythroderma, scleroderma, sisitemu ya lupus erythematosus (SLE), Erythema multiforme, shingles na alopecia areata. Kuvura ingaruka zo kuragwa angioedema nabyo ni byiza. Mu kuvura Chloasma, ubuvuzi rusange bukora hafi ibyumweru 3, bugaragara neza ibyumweru 5, amasomo yiminsi 60. Uhaye umunwa muri dosiye ya 0,25 ~ 0.5 g, kumunsi inshuro 3 ~ 4. Abarwayi bake barashobora kugira isesemi, umunaniro, pruritus, kubura inda, n'ingaruka zimpiswi nyuma yo gukuramo ibimenyetso.
Ibyerekana
Amaraso atandukanye aterwa na acute cyangwa karande, yegereye cyangwa sisitemu yibanze ya hyperfibrinolysis; icyiciro cya kabiri cya hyperfibrinolytike iterwa no gukwirakwiza imitsi y'amaraso. Mubisanzwe ntukoreshe iki gicuruzwa mbere ya heparinisation.
Ihahamuka cyangwa kubaga amaraso mu ngingo no mu ngingo hamwe na plasminogene nyinshi ikora nka prostate, urethra, ibihaha, ubwonko, nyababyeyi, glande adrenal, na tiroyide.
Kurwanya tissue plasminogen ukora (t-PA), streptokinase, na urokinase.
Amaraso ya Fibrinolytike aterwa no gukuramo inda, gutandukana hakiri kare, kubyara no kuvuka kwa amniotic; no kwiyongera kwa menorrhagia iterwa na pathologiya intrauterine fibrinolysis.
Ubwonko bwa neuropathie cerebral maraso yoroheje, nka hemara ya subarachnoid hamwe na aneurysm yo kuva amaraso, ingaruka za Amstat muriyi miterere ni nziza kuruta iyindi miti irwanya fibrinolytike. Hagomba kwitabwaho cyane cyane ibyago byo kurwara ubwonko cyangwa ubwonko bwubwonko.Ku barwayi bakomeye bafite ibimenyetso byo kubaga, iki gicuruzwa gishobora gukoreshwa gusa nkibiyobyabwenge.
Kubuvuzi bwa hereditori angioneurotic edema, irashobora kugabanya umubare nuburemere bwibice.
Ikoreshwa mubarwayi barwaye hémofilia kumaraso yabo akora neza hamwe nabandi biyobyabwenge.
Abarwayi ba Hemophilia bafite ikibazo cya VIII cyangwa ikibazo cya IX kubura amenyo yabo cyangwa kubagwa mu kanwa mugihe cyo kuva amaraso.
