Ibisobanuro bigufi:
CAS nomero ： 69004-03-1
Inzira ya molekulari ： C18H14F3N3O4S
uburemere bwa molekile ： 425.38
Imiterere ya shimi ：
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Toltrazuril |
| URUBANZA No. | 69004-03-1 |
| Ibara | Ifu yera cyangwa hafi yera ifu ya kristaline |
| Icyiciro | Kugaburira Icyiciro |
| Ububiko | Ikidodo cyumye, Ubushyuhe bwicyumba |
| Ubuzima bwa Shelf | Imyaka 2 |
| Koresha | Inka, Inkoko, Imbwa, Ifi, Ifarashi, Ingurube |
| Amapaki | 25kg /ingoma |
Ibisobanuro
Toltrazuril (Baycox®, Procox®) ni umuti wa triazinon ufite antikokiside nini na antiprotozoalactivite. Ntabwo iboneka mubucuruzi muri UnitedStates, ariko iraboneka mubindi bihugu. Irakora cyane mubyiciro byubusambanyi nubusambanyi bwa coccidia ibuza igabana rya kirimbuzi rya schizonts na microga-monts hamwe n imibiri ikora urukuta rwa macrogamonts. Itmay kandi ifite akamaro mukuvura neonatal porcinecoccidiose, EPM, na hepatozoonose ya kine.
Toltrazuril hamwe na metabolite nini ya ponazuril (toltrazuril sulfone, Marquis) ni imiti ya antiprotozoal ishingiye kuri triazine ifite ibikorwa byihariye byo kurwanya indwara ziterwa na coccidial apicomplexan. Toltrazuril ntabwo iboneka muri Amerika.
Gukoresha ibicuruzwa
Ingurube: Toltrazuril yerekanwe kugabanya ibimenyetso bya coccidiose mu ngurube zonsa zanduye bisanzwe iyo umunwa umwe 20-30 mg / kg BWdose ihabwa ingurube ziminsi 3 kugeza kuri 6 (Driesen et al., 1995). Ibimenyetso by’amavuriro byagabanutse kuva kuri 71 bigera kuri 22% by’ingurube zonsa, kandi impiswi na oocyst isohoka nabyo byagabanutse no kuvura umunwa umwe. Ibicuruzwa byemewe bitwara iminsi 77 yo gukuramo mu Bwongereza.
Inyana n'intama: Toltrazuril ikoreshwa mugukumira ibimenyetso byamavuriro ya coccidiose no kugabanya isuka ya coccidia mu nyana nintama nkumuti umwe. Ibihe byo gukuramo mu Bwongereza ni iminsi 63 na 42 ku nyana n'intama.
Imbwa. Macintire n'abandi., 2001). Kubwamahirwe, imbwa nyinshi zavuwe zasubiye inyuma amaherezo zipfa na hepatozoonose. Mubibwana hamwe na Isospora sp. kwandura, kuvura hamwe na 0,45 mg emodepside ifatanije na 9 mg / kg BW toltrazuril (Procox®, Ubuzima bw’inyamaswa za Bayer) igabanya umubare wa oocyst fecal kuri 91.5-100%. Nta tandukaniro ryigeze rimara igihe cyo gucibwamo igihe ubuvuzi bwatangiraga nyuma yo gutangira ibimenyetso byamavuriro mugihe cyo kwandura patenti (Altreuther et al., 2011).
Injangwe: Mu njangwe zanduye mu buryo bwa Isospora spp., Kuvura hamwe n'umuti umwe wo mu kanwa wa emodepside 0,9 mg hamwe na 18 mg / kg BW toltrazuril (Procox®, Bayer AnimalHealth) igabanya isuka ya oocyst ku gipimo cya 96.7-100% iyo itanzwe mugihe cyo kubitegura. gihe (Petry et al., 2011).
Ifarashi: Toltrazuril nayo yakoreshejwe mu kuvura EPM. Uyu muti ufite umutekano, ndetse no kuri dosiye nyinshi. Ubu buryo bwo kuvura busabwa ni 5-10 mg / kg kumunwa muminsi 28. Nuburyo bwiza hamwe na toltrazuril, imikoreshereze yayo yagabanutse kumafarasi kubera ko haboneka imiti yindi miti myiza.
