Ibisobanuro bigufi:
Numero ya CAS: 58-55-9
Inzira ya molekulari: C7H8N4O2
Uburemere bwa molekuline: 180.16
Imiterere ya shimi:
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Theophylline Anhydrous |
| URUBANZA No. | 58-55-9 |
| Kugaragara | umweru kugeza umuhondo wijimyeder |
| Igihagararo: | Ihamye. Ntibishobora gukoreshwa na okiside ikomeye. |
| Amazi meza | 8.3 g / L (20 ºC) |
| Ububiko | 2-8 ° C. |
| Ubuzima bwa Shelf | 2 Yugutwi |
| Amapaki | 25kg / Ingoma |
Ibisobanuro ku bicuruzwa
Theophylline ni methylxanthine ikora nka bronchodilator idakomeye. Ni ingirakamaro mu kuvura karande kandi ntabwo ifasha muburyo bukabije.
Theophylline ni methylxanthine alkaloide ikumira irwanya fosifisiyose (PDE; Ki = 100 μM). Ninindi idahitamo antagonist ya adenosine A yakira (Ki = 14 μM kuri A1 na A2). Theophylline itera kuruhuka imitsi yoroshye ya bronchiole imitsi yoroshye yandujwe na acetylcholine (EC40 = 117 μM; EC80 = 208 μM). Imiti irimo theophylline yakoreshejwe mu kuvura asima n'indwara idakira ifata ibihaha (COPD).
Gusaba
1.Kuvura asima: Theophylline irashobora gufasha kugabanya ibimenyetso bya asima muguhuza ibice bya bronchial no kongera imitsi.
2.Kuvura indwara z'umutima: Theophylline irashobora kuba vasodilator, ifasha kunoza ibimenyetso byindwara z'umutima.
3.Gukangura sisitemu yo hagati yo hagati: Theophylline ikoreshwa mumiti imwe nimwe itera imbaraga za sisitemu yo hagati, itera kuba maso no kwitabwaho.
4.Kugena ibinure bya metabolisme: Theophylline irashobora gutuma ibinure bigabanuka kandi bizera ko bifasha mukugabanya ibiro no kugabanya ibiro.
