Ibisobanuro bigufi:
CAS nomero ： 59-05-2
Inzira ya molekulari ： C.20H22N8O5
uburemere bwa molekile ： 454.45
Imiterere ya shimi ：
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Methotrexate |
| Icyiciro | icyiciro cya farumasi |
| Kugaragara | ifu ya orange-umuhondo ifu ya kristaline. |
| Suzuma | 99% |
| Ubuzima bwa Shelf | Imyaka 2 |
| Gupakira | 25kg / ikarito |
| Ibiranga | Ihamye, ariko yoroheje yumucyo na hygroscopique. Ntibishobora kubangikanya aside ikomeye, imbaraga za okiside ikomeye. |
| Imiterere | Gumana ahantu hijimye, Inert ikirere, Ubike muri firigo, munsi ya -20 ° C. |
Methotrexate ni iki?
Methotrexate yunvikana hydrolysis, okiside n'umucyo. Kudashonga mumazi. Methotrexate ibora mubihe bya acide cyane cyangwa alkaline. Methotrexate ntishobora kubangikanya ibintu bikomeye bya okiside na aside ikomeye.
Methotrexate ni imiti ikoreshwa mu kuvura kanseri, izwi kandi nk'imiti ya cytotoxic. Kugirango ugabanye cytotoxicity yayo, irashobora gukoreshwa ifatanije na calcium leucovorin. Ikoreshwa cyane cyane mu kuvura indwara ya leukemia ikaze (acute lymphocytic leukemia), kanseri y'ibere, malignant mole na choriocarcinoma, kanseri yo mu mutwe no mu ijosi, kanseri y'amagufa, leukemia, umugongo wa meningeal yinjira, kanseri y'ibihaha, kanseri y'imyororokere, kanseri y'umwijima, kwanga psoriasis vulgaris, dermatomyosite, umubiri myosite, ankylose spondylitis inflammation, indwara ya Crohn, psoriasis na psoriatic arthritis, indwara ya Behcet n'indwara ya autoimmune. Methotrexate ni imiti ikingira indwara kandi irashobora gukoreshwa mu koroshya inzira ya rubagimpande hamwe n’ingirakamaro cyane mu kuvura indwara ya sinoviya ya rubagimpande ya rubagimpande kandi niwo muti ukoreshwa cyane mu kuvura indwara za rubagimpande.
Gusaba ivuriro
Nibyiza kuvura leukemia ikaze hamwe nibikorwa byiza kubarwayi babana. Ifite ingaruka nziza mukuvura choriocarcinoma na mole mbi. Ubuyobozi bunini bwa dose bufite akamaro mukuvura osteosarcoma, tissue yoroshye sarcoma, kanseri y'ibihaha, kanseri y'ibere, kanseri y'ibere, na kanseri yintanga. Ifite kandi akamaro mu kuvura kanseri yo mu mutwe no mu ijosi, kanseri y'umwijima na kanseri yo mu gifu. Kwinjiza arterial yibi bicuruzwa bifite goo efficacy mukuvura kanseri yumutwe nijosi na kanseri yumwijima. Ariko, ni gake ikoreshwa mukuvura psoriasis na psoriasis.
