Ibisobanuro bigufi:
CAS nomero ： 126-07-8
Inzira ya molekulari ： C.17H17ClO6
uburemere bwa molekile ： 352.77
Imiterere ya shimi ：
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Griseofulvin |
| Icyiciro | icyiciro cya farumasi |
| Kugaragara | Ifu yera kugeza umuhondo-umweru |
| Suzuma | 99% |
| Ubuzima bwa Shelf | Imyaka 3 |
| Gupakira | 25kg / ikarito |
| Ibiranga | Mubyukuri bidashobora gushonga mumazi, gushonga kubusa muri dimethylformamide no muri tetrachloroethane, gushonga gato muri Ethanol ya anhydrous no muri methanol |
| Imiterere | Komeza ikintu gifunze ahantu humye, gahumeka neza. |
Ibisobanuro rusange bya Griseofulvin
Griseofulvin ni antibiyotike yo mu rwego rutari polyene; irashobora kubuza cyane mitito ya selile fungal kandi ikabangamira synthesis ya ADN ya fungal; irashobora kandi guhambira kuri tubuline kugirango irinde igabana rya selile. Yakoreshejwe mubuvuzi kuva 1958 kandi kuri ubu yakoreshejwe cyane mukuvura indwara zanduye zuruhu na stratum corneum hamwe ningaruka zikomeye zo kubuza Trichophyton rubrum na Trichophyton tonorans, nibindi. Griseofulvin ntabwo ari antibiotique ikoreshwa cyane mubuvuzi. kuvura indwara zanduye zuruhu na cicicle, ariko kandi zikoreshwa mubuhinzi hagamijwe gukumira no kuvura indwara zifata ibihumyo; kurugero, ifite efficacy idasanzwe yo kuvura ubwoko bwa kandidiasis muri pome ishobora gutera kwandura mugihe cyo kwanduza.
Ibimenyetso bya Griseofulvin
Mu buvuzi,iki gicuruzwa kibereye kuvura inzoka zitandukanye, zirimo tinea capitis, tinea barbae, tinea yumubiri, jock itch, tinea yamaguru na onychomycose. Ubwoko butandukanye bwa tinea buvugwa buterwa nibihumyo bitandukanye birimo Trichophyton rubrum, Trichophyton tonorans, Trichophyton mentagrophytes, Fingers Trichophyton, nibindi, na Microsporon audouini, Microsporon canis, Microsporon gypseum na Epidermophyton floccosum, nibindi bikwiye. Iki gicuruzwa ntigikwiye kuvurwa mugihe cyoroheje, indwara zanduye zaho hamwe nibishobora kuvurwa hakoreshejwe imiti igabanya ubukana. Griseofulvin ntabwo ifite akamaro mukuvura indwara zubwoko butandukanye nka Candida, Histoplasma, Actinomyces, ubwoko bwa Sporothrix, Blastomyces, Coccidioides, Nocardio na Cryptococcus kimwe no kuvura tinea vericolor.
Mu buhinzi,iki gicuruzwa cyatangijwe bwa mbere na Brian etal (1951) muguhashya indwara z ibihingwa. Nk’uko ubushakashatsi bwabigaragaje, irashobora gukoreshwa mu gukumira indwara y’imizabibu (melon), kwandura indwara, indwara ya watermelon, anthracnose, indabyo za pome, kubora kwa pome, kubora pome, imyumbati yamenetse, ibyatsi byimeza, ibishishwa bimanika indwara , ifu ya mildew ya roza, chrysanthemums powdery mildew, indabyo ziboze, ibibyimba byinyanya kare, tulip fire blight nizindi ndwara zifata.
