Ubwiza Bwiza Gutanga 99% Ifu ya Albendazole Yera, Ibikoresho Byinyamanswa

Dushingiye ku mbaraga za tekiniki zikomeye kandi duhora dushiraho tekinoloji ihanitse kugirango duhaze icyifuzo cyiza Cyiza Gutanga 99% Ifu Yera ya Albendazole, Ibikoresho byinyamanswa, Turahora dutegereje kuzagirana umubano mwiza mubucuruzi nabaguzi bashya kwisi.
Dushingiye ku mbaraga za tekinike zikomeye kandi duhora dushiraho ikorana buhanga kugirango duhaze icyifuzo cyaUbushinwa Albendazole na Pharmaceutical Chemical, Isosiyete yacu ifite ubuso bwa metero kare 20 000 000. Dufite abakozi barenga 200, itsinda rya tekinike yabigize umwuga, uburambe bwimyaka 15, gukora neza, gukora neza kandi kwizewe, igiciro cyapiganwa nubushobozi buhagije bwo gukora, nuburyo dukomeza abakiriya bacu. Niba ufite ikibazo, wibuke kudatindiganya kutwandikira.

Ibisobanuro

Albendazole (ALBENZA) ni umunwa utangwa mu buryo bwagutse. Ibinini byitwa Albendazole byashyizwe mu rutonde rw’umuryango w’abibumbye wita ku buzima (OMS) by’imiti yingenzi nkumuti wo mu nda wa anthelminthic na antifilarial. Ibinini bya Albendazole byakozwe na Laboratoire y’ubuzima bw’amatungo ya SmithKline kandi byemejwe n’ikigo cy’Amerika gishinzwe ibiryo n’ibiyobyabwenge (FDA) mu 1996.
Albendazole ifite ubushobozi bwo kwica burundu amagi ya whipworm na hookworm ndetse no kwica igice cya amagi ya Ascaris; irashobora kandi kuvanaho ubwoko butandukanye bwa nematode yanduza umubiri winyamanswa, kandi ikagira ingaruka muburyo bwo gukuraho cyangwa kwica mu buryo butaziguye inzoka na cysticerci. Ni ingirakamaro rero mu kuvura hydatide na sisitemu y'imitsi (cysticercose) iterwa no kwanduza inyo z'ingurube, ndetse no mu kuvura inzoka, inzoka, inzoka, nematode trichinella, tapeworm, whipworm na stercoralis nematode.

Imiti ya farumasi

Albendazole ni ubwoko bwa benzimidazole. Ihinduranya vuba muri vivo muri sulfoxide, sulfone na alcool ya 2-polyamine. Irashobora guhitamo kandi bidasubirwaho guhagarika glucose gufata ya nematode yo munda, bityo bikavamo endogenous glycogen igabanuka ryinyo; icyarimwe, irabuza kandi ibikorwa bya reductase ya fumarate, bityo ikabuza kubyara adenosine triphosphate, amaherezo igatera urupfu rwa parasite.
Kimwe na mebendazole, binyuze mugutera gutandukanya microtubules ya cytoplasmeque ya parasite yo munda no guhambira kuri tubuline, itera gufunga ubwikorezi bwo mu nda, bigatuma habaho kwirundanya kwa endocrine ya Golgi; cytoplazme irashonga buhoro buhoro, itera urupfu rwa nyuma rwa parasite.
Iki gicuruzwa kirashobora kwica burundu amagi yinzoka, amagi yinzoka, amagi yintama yintama, amagi ya tapeworm n amagi ya cysticercose kandi byica amagi ya Ascaris.

Imikoreshereze rusange

Albendazole numuti ukoreshwa mukuvura indwara ziterwa na parasite. Irashobora gutangwa kugirango ivure ubwonko budasanzwe (neurocysticercose) cyangwa irashobora gutangwa kugirango ivure indwara ya parasitike itera impiswi zikomeye (microsporidiose).

Gukoresha Ivuriro

Albendazole ifite ibikorwa byinshi byo kurwanya nematode yo munda na cestode, hamwe n'umwijima uhindura Opisthorchis sinensis, Opisthorchis viverrini, na Clonorchis sinensis. Yakoreshejwe kandi neza kurwanya Giardia lamblia. Irakoreshwa henshi kwisi kuvura indwara zo munda. Nibyiza nkumuti umwe wo kuvura asikariyasi, Indwara Nshya na Kera Isi yanduye, na trichuriasis. Kuvura inshuro nyinshi hamwe na albendazole caneradicate pinworm, urudodo, capillariasis, clonorchiasis, n'indwara ya hydatide. Imikorere ya albendazole irwanya imiti (cestode) muri rusange irahinduka kandi idashimishije. Ifite kandi akamaro mu kuvura ubwonko n’umugongo neurocysticercose, cyane cyane iyo itanzwe na dexamethasone.Albendazole irasabwa kuvura gnathostomiasis.

Dushingiye ku mbaraga za tekiniki zikomeye kandi duhora dushiraho tekinoloji ihanitse kugirango duhaze icyifuzo cyiza Cyiza Gutanga 99% Ifu Yera ya Albendazole, Ibikoresho byinyamanswa, Turahora dutegereje kuzagirana umubano mwiza mubucuruzi nabaguzi bashya kwisi.
Ubwiza bwizaUbushinwa Albendazole na Pharmaceutical Chemical, Isosiyete yacu ifite ubuso bwa metero kare 20 000 000. Dufite abakozi barenga 200, itsinda rya tekinike yabigize umwuga, uburambe bwimyaka 15, gukora neza, gukora neza kandi kwizewe, igiciro cyapiganwa nubushobozi buhagije bwo gukora, nuburyo dukomeza abakiriya bacu. Niba ufite ikibazo, wibuke kudatindiganya kutwandikira.