Ibisobanuro bigufi:
Numero ya CAS: 112811-59-3
Inzira ya molekulari: C.19H22FN3O4
uburemere bwa molekile: 375.39
Imiterere ya shimi ：
| Amakuru Yibanze | |
| Izina ryibicuruzwa | 112811-59-3 |
| Icyiciro | Icyiciro cya farumasi |
| Kugaragara | Ifu yera-Yera ifu ya kristaline |
| Suzuma | 99% |
| Ubuzima bwa Shelf | Imyaka 2 |
| Gupakira | 25kg / ingoma |
| Ububiko | Bika ahantu hakonje |
Ibisobanuro ku bicuruzwa
Gatifloxacin ni iy'imiti izwi ku izina rya antibiotique ya quinolone kandi ikoreshwa mu kuvura indwara zikomeye za sinus, ibihaha, cyangwa inkari zandurira mu mibonano mpuzabitsina ndetse n'indwara zandurira mu mibonano mpuzabitsina. Uyu muti urashobora gufatwa mu kanwa, mu buryo bwa tablet, cyangwa no gutera inshinge. Ingaruka mbi ziterwa na zo hamwe na gatifloxacin harimo isesemi, vaginite (kurakara cyangwa gutwika ibyara) ， impiswi, kubabara umutwe, kuzunguruka, no gutera umutima bidasanzwe. Muri rusange, gatifloxacin ikoreshwa mubantu batitabira ubundi buvuzi bwa AOM.
Mu bushakashatsi bumwe, gatifloxacin yagereranijwe na amoxicillin / clavulanate mu kuvura itangazamakuru rya otitis risubirwamo (OM) na AOM mu kunanirwa kwivuza ku bana. Impinja magana atatu na mirongo itanu na bane hamwe n’abana bafite ikibazo cya OM cyangwa AOM bakunze kubona gatifloxacin cyangwa amoxicillin / clavulanate. Ibisubizo byagaragaje ko ibiyobyabwenge byombi byihanganirwa; ingaruka zagaragaye cyane ni impiswi. Abashakashatsi banzuye ko kuvura gatifloxacine rimwe ku munsi byagize akamaro nka amoxicillin / clavulanate kabiri ku munsi. Mu bindi bitabo by’ubuvuzi, gatifloxacin yagaragaye nk'uburyo bwa gatatu bwo kuvura muri AOM.
Imiti ya farumasi
Ikirangantego kirimo Acinetobacter spp na Aeromonas spp, ariko ntabwo ikora cyane kurwanya Zab. aeruginosa hamwe nizindi fermentation Gram-negative inkoni. Irakora cyane kurwanya methicillin-ishobora kwanduzwa na staphylococci kuruta methicilline-idashobora kwihanganira. Irakora kandi kurwanya Chlamydia, Mycoplasma na Legionella spp. kandi ifite ibikorwa bimwe na bimwe birwanya anaerobes.
Hafi yuzuye rwose iyo itanzwe kumunwa kandi ikwirakwizwa cyane mumubiri mubice byinshi byumubiri hamwe namazi. Plasma igice cyubuzima ni 6-8 h. Ibiyobyabwenge birenga 70% bisohoka bidahindutse mu nkari. Kurandura impyiko byagabanutseho 57% mugihe cyo kubura impyiko ziciriritse na 77% mubudahagije bwimpyiko.
Kurambura intera ya QTC mu barwayi bamwe no kwivanga kwa diyabete byatumye imiti ikurwa mu bihugu byinshi kugira ngo ikoreshwe kuri gahunda. Gatifloxacin ikomeje gukoreshwa muri Amerika ya ruguru gusa nk'igisubizo cy'amaso.
Ingaruka
Gatifloxacin yakiriwe neza mu nzira ya gastrointestinal (kuboneka mu kanwa hafi 100%), kandi ubuyobozi bujyanye no gufata amafunguro ya mugitondo yo ku mugabane, 1050 kcal, ntacyo byagize ku kuboneka kwayo. Igipimo gisanzwe ni 400 mg od kandi byombi kumanwa no mumitsi irahari.
Ingaruka rusange
Kwangirika kwanduye amaso
Kurakara amaso
Kubabara amaso
Hindura uburyohe
