Ibisobanuro bigufi:
Uruziga, Oval, Oblong, Triangle, Diamond nuburyo bumwe bwihariye burahari.
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Ibinini bya Folate |
| Andi mazina | Amababi ya Acide Folike, Tablet ya Folate ikora, Tablet ya Acide Folike ikora, nibindi. |
| Icyiciro | Urwego rwibiryo |
| Kugaragara | Nkibisabwa abakiriya Uruziga, Oval, Oblong, Triangle, Diamond nuburyo bumwe bwihariye burahari. |
| Ubuzima bwa Shelf | 2-3years, ukurikije imiterere yububiko |
| Gupakira | Umubare munini, amacupa, udupapuro twa bliste cyangwa ibyo abakiriya bakeneye |
| Imiterere | Bika mu bikoresho byoroshye, birinzwe n'umucyo. |
Ibisobanuro
Ingaruka za aside folike ku binyabuzima zigaragarira cyane cyane mu ngingo zikurikira: kugira uruhare muri metabolisme y'ibintu bikomoka kuri poroteyine; bigira ingaruka ku myororokere y’inyamaswa; bigira ingaruka ku gusohora kwa pancreas; guteza imbere imikurire y’inyamaswa; no kuzamura ubudahangarwa bw'umubiri.
Methyltetrahydrofolate mubisanzwe yerekeza kuri 5-methyltetrahydrofolate, ifite umurimo wo kugaburira umubiri no kuzuza aside folike. 5-Methyltetrahydrofolate ni ikintu gifite imikorere ikora ihindurwamo aside folike ikoresheje urukurikirane rw'ibinyabuzima mu mubiri w'umuntu. Irashobora gukoreshwa mu buryo butaziguye n'umubiri munzira zitandukanye zo guhinduranya kugirango igumane imikorere isanzwe yumubiri, bityo igire uruhare mukugaburira umubiri.
Imikorere
Acide Folike ni ubwoko bwa vitamine B, izwi kandi nka pteroylglutamic aside. 5-methyltetrahydrofolate nintambwe yanyuma muri metabolism no guhindura inzira ya aside folike mumubiri. Kubera imikorere ikora, nayo yitwa gukora. Acide Folike ni metabolike ya aside folike mumubiri.
Kuberako imiterere ya molekuline ya 5-methyltetrahydrofolate ishobora kwinjizwa mu buryo butaziguye n'umubiri bitanyuze mu buryo bworoshye bwo guhindura metabolike, igaragara cyane mu ngirabuzimafatizo z'umubiri. Ugereranije na aside folike, biroroshye kongerera intungamubiri umubiri, cyane cyane kubagore bakeneye kwitegura gutwita nabagore batwite mugihe batwite.
Acide Folike ni imwe muri vitamine zingenzi mu mikurire no kubyara ingirabuzimafatizo. Kubura kwayo bizagira ingaruka kumikorere isanzwe yumubiri wumuntu. Ubuvanganzo bwinshi bwatangaje ko kubura aside folike bifitanye isano itaziguye n'indwara zifata imitsi, anemiya ya megaloblastique, iminwa n'iminwa, kwiheba, ibibyimba n'izindi ndwara.
Imikorere mibi ya Neural (NTDs)
Indwara ya Neural tube malformations (NTDs) nitsinda ryinenge ziterwa no gufunga bituzuye kwifunguro ryimitsi mugihe cyo gukura kwa emboro, harimo anencephaly, encephalocele, spina bifida, nibindi, kandi nimwe mubibazo bikunze kuvuka. Mu 1991, Inama y’ubuvuzi y’Ubwongereza yemeje ku nshuro ya mbere ko kongera aside folike mbere na nyuma yo gutwita bishobora gukumira indwara zandurira mu mibonano mpuzabitsina kandi bikagabanya 50-70%. Ingaruka zo gukumira aside folike kuri NTDs zafashwe nkimwe mubintu byavumbuwe mubuvuzi bishimishije mu mpera z'ikinyejana cya 20.
Anemia ya Megaloblastique (MA)
Anemia ya Megaloblastique (MA) ni ubwoko bwa anemia iterwa no kugabanuka kwa synthesis ya ADN iterwa no kubura aside folike cyangwa vitamine B12. Bikunze kugaragara cyane ku mpinja no ku bagore batwite. Iterambere risanzwe ryuruhinja risaba aside folike nyinshi mumubiri wa nyina. Niba ububiko bwa aside folike bwaragabanutse mugihe cyo kubyara cyangwa kubyara hakiri kare, amaraso make ya megaloblastique azagaragara mu nda na nyina. Nyuma yo kuzuza aside folike, indwara irashobora gukira vuba igakira.
Acide Folike hamwe n'iminwa
Umunwa wuzuye (CLP) ni imwe mu nenge zikunze kuvuka. Impamvu yiminwa niminwa iracyagaragara neza. Kwiyongera kwa aside folike mugihe cyo gutwita hakiri kare byagaragaye ko birinda kuvuka kwabana bafite umunwa wuzuye.
Izindi ndwara
Kubura aside folike birashobora guteza ingaruka mbi kubabyeyi nabana, nko gukuramo inda bisanzwe, kubyara imburagihe, kubyara bike, kutarya inda no kudindira gukura. Ubuvanganzo bwinshi buvuga ko indwara ya Alzheimer, kwiheba, hamwe n’imitsi idasanzwe y’abana bavutse ndetse n’ibindi bikomere bifitanye isano n’ubwonko byose bifitanye isano no kubura aside folike. Byongeye kandi, kubura aside folike bishobora nanone gutera ibibyimba (kanseri y'inda ibyara, kanseri ya bronchial, kanseri yo mu nda, kanseri yibara, n'ibindi), gastrite idakira, colitis, indwara z'umutima n'indwara zifata ubwonko, ndetse n'izindi ndwara nka glossite na gukura nabi. Abantu bakuru babuze aside folike kandi banywa inzoga nyinshi zirashobora guhindura imiterere ya mucosa yo munda.
Porogaramu
1. Abagore mugihe cyo gutegura gutwita no gutwita hakiri kare.
2. Abantu bafite ikibazo cyo kubura amaraso.
3. Abantu bafite homocysteine nyinshi.
