Ibisobanuro bigufi:
CAS nomero ： 24390-14-5
Inzira ya molekulari ： C.24H31ClN2O9
uburemere bwa molekile ： 526.97
Imiterere ya shimi ：
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Doxycycline hyclate |
| Icyiciro | icyiciro cya farumasi |
| Kugaragara | ifu y'umuhondo, hygroscopique kristaline |
| Suzuma | 99% |
| Ubuzima bwa Shelf | Imyaka 2 |
| Gupakira | 25kg / ikarito |
| Imiterere | bibitswe ahantu hakonje kandi humye |
Ibisobanuro bya Doxycycline Hyclate
Doxycycline ni umwe mu bagize itsinda rya antibiyotike ya tetracycline, kandi ikunze gukoreshwa mu kuvura indwara zitandukanye. Hyclate ya Doxycycline ni ifu yumuhondo, hygroscopique ya kristaline, ifata ubusa mu mazi no muri methanol, ikabura gake muri Ethanol (96 ku ijana), gushonga mubisubizo bya hydroxide ya alkali na karubone.
Doxycycline Hyclate ni umunyu wa hyclate ya doxycycline, ni antibiyotike ya tetracycline yagutse. Irabuza intungamubiri za poroteyine za bagiteri guhuza ribosomes. Doxycycline irabuza kandi guhitamo matrix matrix metalloproteinase-8 (MMP-8) na MMP-13 hejuru ya MMP-1 hamwe na 50, 60, na 5% bibujijwe, iyo bikoreshejwe kuri 30 μM. Irashobora gukoreshwa nkubuyobozi bwa sisitemu yo kwerekana imiterere ya gene idasobanutse aho imvugo iterwa no kuba ahari (Tet-On) cyangwa kubura (Tet-Off) ya doxycycline. Imiti irimo doxycycline yakoreshejwe mu kuvura indwara ziterwa na bagiteri no kwirinda malariya.
Imikoreshereze ya Doxycycline hyclate
Doxycycline hyclate ni umwe mu bagize itsinda rya antibiyotike ya tetracycline, kandi ikoreshwa mu kuvura indwara zitandukanye. Ikoreshwa mukuvura chlamydia, rickettsia, mycoplasma n'indwara zimwe na zimwe za spirochete. Irakoreshwa kandi mukubuza matrix metalloproteinase kuri dosiye ya subantimicrobial. Irabuza matrix metalloproteinase kuri dosiye ya subantimicrobial.
Doxycycline hyclate ni intungamubiri ya oxytetracycline. Byakoreshejwe mu kurandura Borrelia burgdorferi na Anaplasma phagocytophilum mu bigega byimbeba no gukuraho amatiku ya Ixode scapularis. Nibikoresho byagutse bikoreshwa muguhagarika matrix metalloproteinase (MMP), nkubwoko bwa 1 kolagenase mubushakashatsi bwerekeye gukira ibikomere no kuvugurura ingirangingo.
