Ibisobanuro bigufi:
CAS nomero 64 1264-72-8
Inzira ya molekulari ： 2 (C.52H98N16O13) .5 (H.2SO4)
uburemere bwa molekile ： 2801.27
Imiterere ya shimi ：
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Sulfate ya Colistine |
| Icyiciro | Kugaburira Icyiciro |
| Kugaragara | Ifu yera cyangwa hafi yera, ifu ya hygroscopique |
| Suzuma | 99% |
| Ubuzima bwa Shelf | Imyaka 2 |
| Gupakira | 20kg / ikarito 20kg / ingoma |
| Imiterere | Ubike kuri -20 ℃ kumwaka umwe（Ifu） |
Ibisobanuro by'ibicuruzwa
Colistine ni cyclic cationic decapeptide ifitanye isano na aside irike ya aside irike, ni iyitsinda rya peptide ya mikorobe ya mikorobe isa nayo. Colistine sulfate ni antibiyotike ya polypeptide ibuza bagiteri-mbi ya bagiteri guhuza lipopolysaccharide na fosifolipide mu ngirabuzimafatizo yo hanze ya bagiteri-mbi.
Sulfate ya Colistine, izwi kandi nka sulfate ya colistine, Christian (Colistin), Polymyxin E (Polymyxin E), antiphytine, ifu yera cyangwa hafi yera yera, impumuro nziza, uburyohe busharira, byoroshye gushonga mumazi, gushonga gato muri methanol, Ethanol, hafi yo gushonga muri acetone, ether, alkali yubusa gushonga gato mumazi. Ihamye muri PH3-7.5. Mycolistin sulfate ikorwa na Bacillus polymyxoides, ifite antibacterial ikomeye kuri bagiteri-mbi. Ikoreshwa mu kuvura indwara zo munda ziterwa na bagiteri-mbi ya bagiteri, kandi ikoreshwa nk'inyongera y'ibiryo hamwe no gukura kugaragara. Guhuza ingaruka za sulfadiazine nibyiza.
Imikorere y'ibicuruzwa
Colistine sulfate granules yateye imbere muburyo bwo gukomera kwibiryo no kwerekana imbaraga nyinshi nubwo byakozwe bitarinze gukoresha ibintu bihenze cyangwa ibikoresho bidasanzwe. By'umwihariko, coluline sulfate granules igizwe ahanini na sulfate ya colistine kandi ifite ibipimo bya diametre ya metero 150 kugeza 1500m, ubuso bwihariye bwa cm 40 kugeza kuri 500 cm2 / g, igihe cyo gutose cyiminota 5 cyangwa munsi yacyo hamwe nubushuhe bwa 10% cyangwa munsi.
Imiti ya farumasi
Colistine ni antibiyotike ya polymyxine. Polymyxine ni polypeptide cationic ihagarika ingirabuzimafatizo ya bagiteri ikoresheje uburyo bwo kumenagura ibintu. Hamwe nogutezimbere ibintu bidafite uburozi buke, nka penisiline yagutse na cephalosporine, ikoreshwa rya polymyxine ryababyeyi ryarahebwe ahanini, usibye kuvura indwara zifata ibihaha zidashobora kwanduza abarwayi barwaye fibrosis.
