Ibisobanuro bigufi:
Numero ya CAS:24729-96-2
Inzira ya molekulari: C.18H34ClN2O8PS
uburemere bwa molekile: 504.96
Imiterere ya shimi ：
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Clindamycin Fosifate |
| Icyiciro | Icyiciro cya Farma |
| Kugaragara | ifu yera |
| Suzuma | 95% |
| Ubuzima bwa Shelf | Imyaka 2 |
| Gupakira | 25kg / ingoma |
| Imiterere | Ihamye, ariko ubike neza. Ntibishobora kubangikanya imbaraga zikomeye za okiside, calcium gluconate, barbiturates, sulfate ya magnesium, fenytoin, vitamine B yo mu itsinda B. |
Ibisobanuro
Clindamycin fosifate ni ester-eruble yamazi ya antibiotique ya semisynthetique yakozwe na 7 (S) -chloro-isimbuza itsinda rya 7 (R) -hydroxyl ryababyeyi antibiotique, lincomycine. Nibikomoka kuri lincomycine (lincosamide). Ifite cyane cyane bacteriostatike yibikorwa bya Gram-positif aerobes hamwe na anaerobicbacteria. Ni antibiyotike yibanze ikoreshwa mukuvura indwara. Ibi bishobora kuba birimo kwandura inzira zubuhumekero, septicemia, peritonitis n'indwara zamagufwa. Irakoreshwa kandi mu kuvura acne igereranije kandi ikabije.
Koresha
Clindamycin fosifate ikoreshwa hejuru yonyine cyangwa ifatanije na benzoyl peroxide mukuvura acne vulgaris inflammatory. Mugupima inyungu zishobora guterwa nubuvuzi bwa clindamycin, hagomba gutekerezwa ingaruka zikomeye za GI zijyanye nibiyobyabwenge. Ubuvuzi bwa acne vulgaris bugomba kuba bwihariye kandi bugahinduka kenshi bitewe nubwoko bwibisebe byiganjemo nigisubizo cyo kuvura. Kurwanya indwara zanduye, harimo na clindamycin, muri rusange bigira akamaro mu kuvura acne yoroheje cyangwa yoroheje. Ariko, gukoresha imiti igabanya ubukana nka mitiweli irashobora gutuma barwanya bagiteri; iyi myigaragambyo ifitanye isano no kugabanuka kwamavuriro.Topical clindamycin ni ingirakamaro cyane iyo ikoreshejwe na benzoyl peroxide cyangwa retinoide yibanze. Ibyavuye mu bushakashatsi bw’amavuriro byerekana ko kuvura bivanze bigabanya kugabanuka kwinshi kwa 50-70%.
Clindamycin 2-fosifate ni aa umunyu wa clincamycin, lincosamide ya kimwe cya kabiri. Umunyu utegurwa na fosifora ihitamo ya 2-hydroxy moisite yisukari ya clindamycin. Intangiriro ya fosifate itanga uburyo bwiza bwo gukemura ibibazo byo gutera inshinge. Kimwe nabandi bagize umuryango wa lincosamide, clindamycin 2-fosifate ni antibiyotike yagutse ifite ibikorwa byo kurwanya bagiteri ya anaerobic na protozoans. Clindamycin ikora ihuza 23S ribosomal subunit, ikabuza synthesis.
