Ibisobanuro bigufi:
CAS nomero ： 7177-48-2
Inzira ya molekulari ： C.16H25N3O7S
uburemere bwa molekile ： 403.45
Imiterere ya shimi ：
| Amakuru Yibanze | |
| Izina ryibicuruzwa | Ampicillin |
| Icyiciro | Icyiciro cya farumasi |
| Kugaragara | Ifu yera cyangwa hafi yera, ifu ya kristu |
| Suzuma | |
| Ubuzima bwa Shelf | Imyaka 2 |
| Gupakira | 25kg / ingoma |
| Imiterere | bibitswe ahantu hakonje kandi humye |
Ibisobanuro
Nka tsinda rya penisiline ya antibiotike ya beta-lactam, Ampicillin ni yo ya mbere yagutse ya penisiline yagutse, ifite ibikorwa bya vitro irwanya Gram-positif na Gram-negative aerobic na bacteri za anaerobic, zikoreshwa cyane mu gukumira no kuvura indwara ziterwa na bagiteri z’ubuhumekero, inkari tract, ugutwi hagati, sinus, igifu n'amara, uruhago, nimpyiko, nibindi biterwa na bagiteri zanduye. Irakoreshwa kandi mu kuvura gonorrhea itagoranye, meningite, salmonellose ya endocarditis, nizindi ndwara zikomeye binyuze mu kanwa, gutera inshinge cyangwa no kwinjiza imitsi. Kimwe na antibiyotike zose, ntabwo zifite akamaro ko kuvura indwara zanduye.
Ampicillin ikora mukwica bagiteri cyangwa ikabuza gukura. Nyuma yo kwinjira muri Gram-positif na Gram-negative bacteria, ikora nka inhibitor idasubirwaho ya enzyme transpeptidase ikenerwa na bagiteri kugirango ikore urukuta rw'akagari, bikaviramo guhagarika urukuta rw'utugingo ngengabuzima kandi amaherezo biganisha kuri lysis selile.
Igikorwa cya mikorobe
Ampicillin ntigikora cyane kurenza benzylpenicillin irwanya bagiteri nyinshi za Gram-positif ariko ikora cyane kuri E. faecalis. MRSA n'imirongo ya Str. umusonga hamwe no kugabanya kwandura benzylpenicillin birwanya. Itsinda ryinshi D streptococci, anaerobic Gram-nziza ya cocci na bacilli, harimo L. monocytogène, Actinomyces spp. na Arachnia spp., birashoboka. Mycobacteria na nocardia birwanya.
Ampicillin ifite ibikorwa bisa na benzylpenicillin kurwanya N. gonorrhoeae, N. meningitidis na Mor. catarrhalis. Ikora inshuro 2-8 kurenza benzylpenicilline irwanya ibicurane bya H. na Enterobacteriaceae nyinshi, ariko β-lactamase itanga imiti irwanya. Pseudomonas spp. birwanya, ariko Bordetella, Brucella, Legionella na Campylobacter spp. akenshi birashoboka. Gram-mbi zimwe za anaerobes nka Prevotella melaninogenica na Fusobacterium spp. birashoboka, ariko B. fragilis irwanya, kimwe na mycoplasmas na rickettsiae.
Igikorwa cyo kurwanya icyiciro cya molekile A β-lactamase itanga amoko ya staphylococci, gonococci, ibicurane bya H., Mor. catarrhalis, Enterobacteriaceae na B. fragilis zimwe na zimwe zongerwamo imbaraga na β-lactamase inhibitor, cyane cyane aside clavulanic.
Igikorwa cyacyo cya bagiteri gisa na benzylpenicillin. Imikoreshereze ya bactericidal ibaho hamwe na aminoglycoside irwanya E. faecalis na enterobacteria nyinshi, hamwe na mecillinam kurwanya enterobacteria nyinshi zirwanya ampisiline.
